This large desert unit occupies the southeastern corner of the state, providing hunting for California bighorn sheep, antelope, mule deer and elk.

Famous for trophy-size mule deer in the Trout Creek Mountains, this unit also produces some big bucks in other places, but hunting is difficult with low deer numbers.

This sprawling desert unit covers the southeastern corner of Oregon and contains several mountain ranges, including part of the Trout Creek Mountains, which run into Nevada, the Oregon Canyon Mountains and the Blue Mountains. Topography is rough and rugged in places, flat and featureless in others. Some mountains feature sheer basalt faces. Much of the area is wilderness, most of that included in a number of wilderness study areas.

Most of the unit is open and treeless, much of it covered by sagebrush, rabbitbrush and other low desert shrubs, forbs and grasses. Junipers, mahoganies, serviceberries and mahoganies grow on hills with aspens in places. A few wet areas have alders, cottonwoods and willows.

Private land is minimal in this unit, which is mostly controlled by the BLM. The main roads are U.S. 95, which bisects the unit from north to south and runs along part of the northern boundary; State Highway 205 along the western edge, and Whitehorse Ranch Lane, which connects U.S. 95 and State Highway 205. A network of dirt and gravel roads provide access to much of the interior. No vehicles are allowed in wilderness and wilderness study areas, which comprise a large part of the unit. These include Table Mountain, Wildcat Canyon, Alvord Desert, Twelve Mile Creek, Bowden Hills, Fifteen Mile Creek, Mahogany Ridge, Upper West Little Owyhee and Red Mountain wilderness study areas. Fort McDermitt Indian Reservation on the Nevada line is closed to public hunting.

This is one of the most isolated game management units in America with no nearby towns of any size and few designated campsites. Almost all hunters camp along dirt roads except for those who backpack into wilderness sites.